Liprins and outs
نویسندگان
چکیده
منابع مشابه
Getting a GRIP on Liprins
Two papers in this issue of Neuron add a new dimension to our understanding of liprin and LAR RPTP function during synapse formation. present evidence that Dliprin-alpha interacts with Dlar to regulate presynaptic morphogenesis of the Drosophila neuromuscular junction. demonstrate that mammalian liprin-alpha1 forms a complex with the PDZ protein GRIP and LAR in both pre- and postsynaptic compar...
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Liprin-α proteins are adaptors that interact with the receptor protein tyrosine phosphatase leukocyte common antigen-related (LAR) and other synaptic proteins to promote synaptic partner selection and active zone assembly. Liprin-β proteins bind to and share homology with Liprin-α proteins, but their functions at the synapse are unknown. The Drosophila genome encodes single Liprin-α and Liprin-...
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ژورنال
عنوان ژورنال: Nature Reviews Neuroscience
سال: 2002
ISSN: 1471-003X,1471-0048
DOI: 10.1038/nrn830